Topical Finasteride for Hair Loss | Happy Head Minoxidil Foam vs Liquid: Which Is Better? - Strut Blog There are some challenges associated with switching from topical to oral minoxidil. In general, topical formulations carry less risk of systemic (whole-body) side effects than oral capsules or tablets, but more studies need to be done to confirm this. While both prevent hair loss and stimulate hair growth, one does it at the topical level while the other is a hormonal medicine that prevents hair loss at its source. View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. Oral finasteride was found to be more effective than minoxidil in patients with moderately severe AGA [6]. Low-dose oral Minoxidil for hair loss a maximum dose of one diuretic and two other antihypertensive medications) and have had no success. if you are a non responder to topical thats just the luck of the draw. For those getting side effects from oral Minoxidil or fearful of taking it, topical Minoxidil is always a good alternative. Topical Finasteride, Or Oral Finasteride...? Topical ... A Systematic Review of Topical Finasteride in the ... Oral Minoxidil vs Topical Minoxidil Which is Better ... It is a condition which may cause cosmetic and psychosocial problems in androgen-dependent cases. Logically, the topical will only work in the area it is applied, while the oral covers the entire scalp. In the study, twelve participants experienced adverse reactions, which represents 29.3% of the entire clinical trial. [] However, in cases of non-responders and in patients developing irritant or allergic contact dermatitis to the topical formulation, oral minoxidil (OM) can be an option of choice. Topical minoxidil 2-5%, oral finasteride, and low-level laser therapy are current the standard first-line treatments for androgenetic alopecia (AGA). As of the moment, there seem to be more studies looking at applying topical finasteride and dutasteride together than testing either individually. More recently, low doses of oral minoxidil have been used "off-label" to help patients with androgenetic alopecia who prefer daily oral administration .   Oral minoxidil is available only by prescription. Dislikes Received: 0. Good luck. Anybody here reccomend oral minoxidil over topical? The study found that approximately 84 percent of the participants who were . Topical finasteride may not be for everyone. Minoxidil and finasteride are different medications designed for different purposes. Oral minoxidil vs topical minoxidil pros and cons. Just because you may now only have frontal or crown balding, don't be fooled as the early miniaturization may be all over your scalp including some of the area you do not recognize the miniaturization as it will be less than 50% of the hairy areas. They branded this new version 1988 as Rogaine. Not everybody is blessed with good enzymes in their scalp but the liver is pretty much a processing sure thing so more people are likely to respond. The baseline in the topical minoxidil group was 163.2 hairs per cm2, and at the end of the 24-week trial, it went up to 176.3 hairs per cm2. The men were randomized to receive dutasteride 0.02, 0.1, or 0.5 mg/day, finasteride 1 mg/day, or placebo. Side effects of oral minoxidil therapy are dose related and include low blood pressure, increased heart rate and fluid retention (see page 3). Like any other drug, minoxidil has side effects, but none of them are sexual. Finasteride is more commonly known for its tablet form to treat benign prostatic hyperplasia (BPH), brand name Proscar and male pattern hair loss (alopecia), brand name Propecia. How Rogaine (Minoxidil) Works. The first group received once-daily oral finasteride (1 mg/d), while the second group received topical 2% minoxidil (1 mL twice daily). Dutasteride 0.5 mg was found to be superior to finasteride 1 mg at weeks 12 and 24 at . Since 1997, topical minoxidil has been available over the counter as a generic and under a wide variety of brand names. shedding may occur if there was previous regrowth. recommend combining oral Finasteride with topical Minoxidil . 15 male patients were asked to apply the solution daily for nine months and were given the option of adding three further components to their treatment protocol: 1) oral FNS 1 mg daily 2) topical MNX . In a retrospective assessment and prospective crossover cohort study of 50 male between 20 to 40 years old by Chandrashekar et al. Discover the magic of the internet at Imgur, a community powered entertainment destination. Minoxidil (topical aerosol) 1 ML topical foam (usually 5% concentration) ~60%. Patient 1: Dutasteride injections plus oral Dutasteride plus 5% topical Minoxidil at 12-months. Edited January 5 by ciaus 2 Melvin- Moderator Minoxidil has to be converted by enzyme activity to be utilized by the body. Results showed that 80% to 84.4% of these patients maintained good hair density while on the topical combination of minoxidil 5% . Ultimately, the team concluded that both groups — oral and topical — saw similar results. In this study 26 women received oral minoxidil and 26 women received topical minoxidil. Topical vs Oral Minoxidil? Welcome to the National Library of Medicine, the world's largest biomedical library and the center of biomedical informatics and computational biology at NIH. So, if you don't have any oral Finasteride side effects then you can take it and include 5% topical Minoxidil. Some patients followed with this medication immediately, some took an 8-12 month break before starting the pure topical preparation. What forms do finasteride and minoxidil come in? Like other medicinal solutions for hair loss - such as the Minoxidil solution - topical Finasteride is applied to the local area, i.e. A novel combination topical treatment by the name NuH Hair [topical FNS, dutasteride and minoxidil (MNX)], was formulated by Rafi and Katz (2011). Pretibial edema occurred in 4% of participants in the oral minoxidil group. While this makes the process of application slightly trickier than oral medication, it does mean that the effects are felt more locally. The 1mg Minoxidil oral tablet is a very strange product to use for the treatment of male pattern baldness. Lift your spirits with funny jokes, trending memes, entertaining gifs, inspiring stories, viral videos, and so much more. Topical Minoxidil vs Oral Minoxidil Study In a recent study published in the Journal of the American Academy of Dermatology, a 24-week randomized study was done on fifty-two women suffering from female pattern hair loss. Five patients took a break of 8-12 months in between oral and topical therapy. It was developed all the way back in the '50s. Minoxidil as a Hair Loss Treatment. double‐blind controlled study of the efficacy and safety of topical solution of 0.25% finasteride admixed with 3% minoxidil vs. 3% minoxidil solution in the treatment of male androgenetic alopecia. Abstract. Taking a tablet is the easiest method of a treatment. Frankly, taking an oral form of minoxidil poses various issues (that are not generally associated with the topical version) and does not boast any tested values with regard to scalp hair. Topical minoxidil is used on the scalp by spraying the liquid solution or foam onto the scalp and massaging it in. It was observed that there were no significant differences between the efficacy of aqueous-based topical 2% nanosuspension of minoxidil and the commercial product in the treatment of AGA ( P > 0.05). Originally used to treat high blood pressure, Rogaine is . Furthermore, it may help to discuss these issues . Prescribed for Alopecia. the scalp, as a spray or lotion. In a 2002 study researching strength effectiveness, researchers found after 48 weeks, the group using 5% minoxidil had 45% more hair growth vs. those using 2% minoxidil. A 120-week study of male subjects with androgenetic alopecia showed that minoxidil was statistically significantly superior to the placebo in increasing hair count. It combines FDA-approved meds — finasteride and minoxidil — that are clinically proven to be most effective when used together, into a single solution that can be easily applied to your scalp. Below are some great hair regrowth results of men who took topical Minoxidil 5% and Dutasteride. A 2014 study conducted over 29 weeks in 917 men with AGA found oral dutasteride to be more effective than finasteride for the treatment of hair loss. INTRODUCTION. Read more; Disclaimer: The purpose of this website is to provide the public with general information on hair restoration and related medical topics.Information provided on this site should not be used for medical diagnosis and/or treatment. Roman - only $12 per month. When this side effect was seen, Minoxidil refined the product after much testing. According to Mayo Clinic, minoxidil topical is an over-the-counter medication. However, studies describing their effects in Chinese individuals are scarce. In other words, you do not need a prescription for minoxidil topical in the US or the UK. 4. In this open, randomized and comparative study we evaluated the efficacy of oral finasteride and 5% topical minoxidil treatment for 12 months in 65 male patients with mild to severe AGA. Minoxidil in an oral formulation has been previously used in general medicine for the treatment of severe and uncontrolled hypertension at a dose of 10-40 mg [ 1 ]. Side effects of oral minoxidil therapy are dose related and include low blood pressure, increased heart rate and fluid retention (see page 3). Scalp pruritus affected 19% of participants in the topical minoxidil group. It's to be used twice a day preferable in the morning and evening everyday. First, the patient uses a pill and does not need to use something that potentially affects how the hair looks day to day. There isn't much research comparing topical finasteride and dutasteride. In addition, oral minoxidil has also been investigated by the medical community as a potential agent for male pattern hair loss. DHT in the scalp causes miniaturization of hair follicles in patients suffering from androgenetic alopecia. Prices On average, the cost for oral minoxidil tablets of 2.5 mg is $40 for a supply of 100 tabs. All in all, yes. Aims and Objectives: This study compared Topical Minoxidil 5%+Finasteride 0.1% combination (Group A) and Topical Minoxidil 5%+Oral Finasteride 1 mg/day (Group B) in treating Male . Second, there is not clinical data and research studies that show that the combination of oral and topical Finasteride and topical and oral Minoxidil better results vs oral Finasteride and 5% topical Minoxidil only. Journal of the European Academy of Dermatology and Venereology, 32(12 . Can women use topical finasteride? However, this is not the case with oral minoxidil. A New Study Comparing 5% Minoxidil vs 1 % Topical Spironolactone vs Combined Treatment. Between the two, Minoxidil has been around longer. Topical minoxidil is received very well by the general population, with a tiny percentage of men and women experiencing adverse reactions. At the end of the 24 weeks, oral minoxidil total hair had gone up to 184.7 per cm2. The treatment was randomized, and the women were given 1 mg of oral minoxidil or 5 % of topical minoxidil. research confirms that it is more effective. cons I've heard: not good for your heart. RCT of 50 male patients treated with topical minoxidil + oral finasteride for 2 years THEN followed by topical medication only consisting of topical minoxidil + topical finasteride. Without doubt, oral finasteride offers a far greater convenience. Some studies show that higher concentrations of minoxidil are the most effective for hair growth. Oral minoxidil comes in a form of a tablet. While the increase in total hair density was higher in the OM group (12% vs 7.2%), the difference was not statistically significant (P=.10). It is much more effective than minoxidil alone, and it is more cost effective than taking oral finasteride.". Its main purpose was as an antihypertensive agent. Oral vs Topical Finasteride Research. Oral minoxidil was found to be an effective and well-tolerated treatment alternative for healthy patients having difficulty with topical formulations. The study showed that the baseline for total hair per square centimeter (cm2) in the oral minoxidil group was 164.6. Even though topical minoxidil is one of the most established treatment options for hair loss, a recent study shows that low doses of oral minoxidil might be a helpful adjunct treatment for female pattern hair loss (1). Updated to include the latest in surgical hair restoration, FUE, medical treatments, hair cloning and laser therapy. I've heard people microdosing it at 2.5mg. Oral Minoxidil tablets were used by Ashley and Martin briefly in the early 1990s when standard topical Minoxidil treatments were not strong enough to achieve a decent result. It works as a direct vasodilator, and it's still used in patients with resistant hypertension. Typically, topical minoxidil is safer than oral minoxidil when you are considering higher dosages. One of the main causes of hair loss is Dihydrotestosterone (DHT). minoxidil topical may also be used for purposes not listed in this medication guide. Hair loss is a common problem that can affect both men and women. At the 12 month mark, the participants were asked if they would like to continue treatment for another year. The difference was not statistically significant but the oral minoxidil group also had less hair shedding. Oral minoxidil for hair loss At Salford Royal, patients are considered eligible for oral minoxidil treatment if their hair loss has not responded to topical minoxidil or if these products are not tolerated. A new study by Raouf and colleagues from Egypt set out to compare the benefits of 5 % topical minoxidil gel, 1 % topical spironolactone gel and a combined 5% minoxidil/1 % spironolactone gel. Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. Minoxidil is a topical treatment applied to your scalp twice a day. But if you have tried minoxidil and didn't receive good results, you should definitely try the topical finasteride. No incidence of decreased sexual desire, performance, or sperm count were reported among the patients using topical finasteride. Oral finasteride was suggested to have some potential risks such as gynecomastia, feminization, and impotence [3]. The first group received once-daily oral finasteride (1 mg/d), while the second group received topical 2% minoxidil (1 mL twice daily). 83% of the finasteride-treated group and 81% of the . I'm trying to find out more about the side effects of long term use of this treatment. Articles:Oral vs topical minoxidil study:https://linkinghub.elsevier.com/retrieve/pii/S0190962219326660Heart rate and mortality:https://www.ncbi.nlm.nih.gov/. It's more advantageous to investigate using the 2% of 5% version of topical minoxidil to fight hair loss. Keeps - only $22.50 per month. Each group continued treatment for 12 months. Some people find using oral medications easier than lotion. At the 12 month mark, the participants were asked if they would like to continue treatment for another year. The use of minoxidil topical for hair growth has been proven to be good. Oral minoxidil was originally used to treat refractory hypertension, while the topical formulation, commonly known as Rogaine, was developed in 1987 for male and female pattern hair loss. The benefit of oral minoxidil over topical minoxidil is several fold. I started minoxidil at around the same time I even began checking my blood work (about 2 years ago), so to discern whats causing it may mean I'll go off it for a few months to see. And if you want to increase your odds to 94% from the percentages above, the same clinical study (and many others!) . See the testimonial page here. Poor response to topical minoxidil may occur in individuals with low levels of sulfotransferase enzyme in the hair follicle, which is required to convert the pro-drug . In this randomized comparative study, 52 women with female pattern hair loss (Sinclair's stage 2-4) received oral minoxidil (OM) 1 mg or topical minoxidil (TM) 5% (1 mL) once daily for 24 weeks. Side Effects of Oral Minoxidil. There is some chance that I naturally have a lower WBC count and the topical minoxidil I apply twice daily for the most part may be pushing it slightly out of range. Minoxidil comes in 2% and 5% formulas. Minoxidil is a topical formulation that was first developed as an oral tablet for the treatment of hypertension . DHT Reduction in Scalp and Serum (blood) / Oral vs. Topical finasteride. Unlike Propecia, Rogaine works by stimulating the hair follicle itself to help encourage hair regrowth. Their formulations are personalized, meaning that exact . minoxidil was first introduced as an oral medication for the treatment of severe and recalcitrant hypertension in the 1970s.1coincidentally, physicians observed hair regrowth and generalized hypertrichosis in balding patients, which led to the development of a topical minoxidil formulation for treating androgenetic alopecia (aga) first in male … Topical vs. oral finasteride for hair loss. 7 (2017), all 50 patients used minoxidil 5% and oral 1mg finasteride for 2 years.They then stopped and their treatment differed. While being tested, one of the side effects was increased hair growth. 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